BxPC-3

The BxPC-3 cell line is a well-known and widely used cell line in cancer research, particularly in pancreatic cancer research. It was established in 1985 from the primary tumor of a 61-year-old Caucasian male with pancreatic adenocarcinoma. The BxPC-3 cells are characterized by their epithelial morphology and ability to form tumors in immunodeficient mice, making them a valuable model for studying pancreatic cancer biology and testing potential treatments.

Researchers have extensively utilized the BxPC-3 cell line to investigate the molecular mechanisms underlying pancreatic cancer development and progression. Studies with this cell line have contributed to our understanding of the genetic alterations, signaling pathways, and tumor microenvironment interactions that drive pancreatic cancer growth and metastasis.

Overall, the BxPC-3 cell line has been instrumental in advancing our understanding of pancreatic cancer and has been a valuable tool for preclinical drug development and testing. Its utility in studying the biology of this challenging cancer underscores its significance in cancer research.