HL-60 Promyelocytic Leukemia Cells (HL-60)

HL-60 is a human promyelocytic leukemia cell line that was first isolated from the peripheral blood of a 36-year-old female patient with acute promyelocytic leukemia in 1977. These cells have since become a prominent model system for studying myeloid leukemia, cell differentiation, and cancer biology in general. HL-60 cells exhibit characteristics of both myeloblasts and promyelocytes, making them a valuable tool for investigating the differentiation process of myeloid cells.

Overall, the HL-60 cell line has played a crucial role in advancing our understanding of leukemia biology and has been a key tool in the development of new therapies for this disease. Its versatility and relevance to cancer research continue to make it a popular choice for scientists studying hematologic malignancies and cell differentiation processes.