T-47D are epithelial cells isolated from a pleural effusion obtained from a 54-year-old female patient with an infiltrating ductal carcinoma of the breast. T-47D cell line is characterized by its estrogen receptor-positive (ER+) status, making it a valuable tool for studying hormone-responsive breast cancer. These cells exhibit high levels of both estrogen and progesterone receptors, allowing for the investigation of hormone-mediated signaling pathways and the effects of hormone therapies.
In addition to their hormone receptor status, T-47D cells have been found to exhibit characteristics of luminal subtype breast cancer, making them a relevant model for studying this particular subtype of the disease.
Overall, the T-47D cell line serves as a valuable tool for researchers looking to better understand the molecular mechanisms underlying breast cancer development and progression, as well as for testing potential therapeutic interventions.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI325Hu11 | Human T-47D | T-47D cell line is widely used in research to investigate the molecular mechanisms underlying breast cancer progression, hormone signaling pathways, drug response, and potential therapeutic targets. |
| Extracts | n/a | Extract of T-47D | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | n/a | Medium for T-47D (If Necessary) | Cell Culture Medium Customized Service Offer |