BT-474

The BT474 cell line is a widely studied human breast cancer cell line that was originally derived from a ductal carcinoma in situ (DCIS) lesion in the breast of a 56-year-old patient. BT474 cells are known for their luminal-like characteristics and high expression of the estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2). These receptors play crucial roles in breast cancer development and progression, making the BT474 cell line a valuable model for studying hormone-dependent and HER2-positive breast cancers.

BT474 cell line serves as a valuable tool for studying hormone-dependent and HER2-positive breast cancers, providing insights into the underlying mechanisms of tumor growth, progression, and response to therapy. Its unique characteristics make BT474 cells a versatile model for preclinical research, drug screening, and the development of personalized treatment strategies for patients with breast cancer.


Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI324Hu11 Human BT-474 BT-474 cell line is commonly used to study the biology and treatment of breast cancer, as well as to investigate the mechanisms of drug resistance and metastasis in this disease.
Extracts n/a Extract of BT-474 Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for BT-474 (If Necessary) Cell Culture Medium Customized Service Offer