Conjunctival Goblet Cells (CGC)

Conjunctival goblet cells are specialized cells found in the conjunctiva, which is the thin, transparent membrane that covers the white part of the eye and the inner surface of the eyelids. These cells produce and secrete mucin, a gel-like substance that helps to lubricate and protect the surface of the eye.

Goblet cells play a crucial role in maintaining the health of the ocular surface by forming a protective barrier against environmental irritants, pathogens, and dryness. They also contribute to the maintenance of the tear film, which helps to keep the eye moist and free from infections.

In some eye conditions such as dry eye disease, allergies, or infections, there may be a dysfunction or decrease in the number of goblet cells, leading to symptoms such as dryness, redness, and irritation. Therefore, understanding the role of conjunctival goblet cells is important for the management of various ocular disorders.