Pulmonary Artery Smooth Muscle Cells (PASMC)

Vascular smooth muscle refers to the particular type of smooth muscle found within, and composing the majority of the wall of blood vessels. Vascular smooth muscle contracts or relaxes to change both the volume of blood vessels and the local blood pressure,  Thus the main function of vascular smooth muscle tone is to regulate the caliber of the blood vessels in the body. Acute hypoxia causes pulmonary vasoconstriction in part by inhibiting voltage-gated K(+) (Kv) channel activity in pulmonary artery smooth muscle cells (PASMC). Study shows that a hypoxia-sensitive mechanism essential for inhibiting KCNA5 channel activity is exclusively present in PASMC. The divergent effect of hypoxia on I(K(V)) in PASMC and MASMC also may be due to different expression levels of KCNA5 channels. Studies indicate that cultured pulmonary artery smooth muscle cells can be used in the study of vascular diseases, and play an important role in the new treatment methods of pulmonary vascular disease.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI141Hu01 Primary Human Pulmonary Artery Smooth Muscle Cells (PASMC) Primary Cells
Extracts n/a Extract of Pulmonary Artery Smooth Muscle Cells (PASMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Pulmonary Artery Smooth Muscle Cells (PASMC) (If Necessary) Cell Culture Medium Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI141Mu01 Primary Mouse Pulmonary Artery Smooth Muscle Cells (PASMC) Primary Cells
Extracts n/a Extract of Pulmonary Artery Smooth Muscle Cells (PASMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums MSI141Mu11 Medium for Mouse Pulmonary Artery Smooth Muscle Cells (PASMC) For Mouse Pulmonary Artery Smooth Muscle Cells (PASMC)

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI141Ra01 Primary Rat Pulmonary Artery Smooth Muscle Cells (PASMC) Primary Cells
Extracts n/a Extract of Pulmonary Artery Smooth Muscle Cells (PASMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums n/a Medium for Pulmonary Artery Smooth Muscle Cells (PASMC) (If Necessary) Cell Culture Medium Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Cells CSI141Rb01 Primary Rabbit Pulmonary Artery Smooth Muscle Cells (PASMC) For research use only. It is not approved for human or animal use, or for applications in in vitro diganostic procedures.
Extracts n/a Extract of Pulmonary Artery Smooth Muscle Cells (PASMC) Total Protein/DNA/RNA Extract Customized Service Offer
Mediums MSI141Rb11 Medium for Rabbit Pulmonary Artery Smooth Muscle Cells (PASMC) Complete Medium for Rabbit Pulmonary Artery Smooth Muscle Cells (PASMC)