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Fibroblasts have an important structural role in the spleen, as they provide a scaffold of extracellular matrix in which cells of the immune system reside. Interestingly, 50-65% of the splenic fibroblasts expressed the Thy-1 antigen, while a subpopulation of Thy-1-negative fibroblasts existed.This suggests that the Thy-1- fibroblasts may present antigen to T lymphocytes in vivo under inflammatory conditions. Thus, splenic fibroblasts (SF) are a heterogeneous and dynamic cell type poised in an immunologically relevant location to interact with bone marrow-derived cells under normal and fibrotic conditions.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI094Hu01 | Primary Human Splenic Fibroblasts (SF) | Primary Cells |
| Extracts | n/a | Extract of Splenic Fibroblasts (SF) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | n/a | Medium for Splenic Fibroblasts (SF) (If Necessary) | Cell Culture Medium Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI094Mu01 | Primary Mouse Splenic Fibroblasts (SF) | An ideal culture model for study of splenic disease. |
| Extracts | n/a | Extract of Splenic Fibroblasts (SF) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | MSI094Mu11 | Medium for Mouse Splenic Fibroblasts (SF) | Medium for Mouse Splenic Fibroblasts |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI094Ra01 | Primary Rat Splenic Fibroblasts (SF) | Primary Cells |
| Extracts | n/a | Extract of Splenic Fibroblasts (SF) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | MSI094Ra11 | Medium for Rat Splenic Fibroblasts (SF) | Medium for Rat Splenic Fibroblasts |
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI094Rb01 | Primary Rabbit Splenic Fibroblasts (SF) | Primary Cells |
| Extracts | n/a | Extract of Splenic Fibroblasts (SF) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | MSI094Rb11 | Medium for Rabbit Splenic Fibroblasts (SF) | Medium for Rabbit Splenic Fibroblasts |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI094Ca01 | Primary Canine Splenic Fibroblasts (SF) | For research use only. It is not approved for human or animal use, or for applications in in vitro diganostic procedures. |
| Extracts | n/a | Extract of Splenic Fibroblasts (SF) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | MSI094Ca11 | Medium for Canine Splenic Fibroblasts (SF) | Medium for Canine Splenic Fibroblasts |