Nephronectin (NPNT)

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EGFL6L; POEM; Preosteoblast EGF-like repeat protein with MAM domain; Protein EGFL6-like

Nephronectin (NPNT)
Nephronectin contains 561 amino acids. In situ hybridization detected nephronectin in the developing mouse kidney and in several other tissues and organs. Expression appeared particularly prominent at epithelial-mesenchymal interfaces in tissues undergoing morphogenesis.
The deduced 565- and 582-amino acid proteins have calculated molecular masses of 61.9 and 64.0 kD, respectively. Both proteins contain an N-terminal signal sequence, followed by 5 EGF domains, and a C-terminal MAM domain. They also contain an RGD integrin-binding site, a potential glycosylation site, and a potential tyrosine phosphorylation site. EGF repeats 2, 4, and 5 contain Ca(2+)-binding EGF domains. In the longer variant, the 17 additional amino acids are inserted N-terminal to the first EGF domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH522Hu01 Recombinant Nephronectin (NPNT) Positive Control; Immunogen; SDS-PAGE; WB.
RPH522Hu02 Recombinant Nephronectin (NPNT) Positive Control; Immunogen; SDS-PAGE; WB.
APH522Hu01 Active Nephronectin (NPNT) Cell culture; Activity Assays.
RPH522Hu03 Recombinant Nephronectin (NPNT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH522Hu01 Polyclonal Antibody to Nephronectin (NPNT) WB; IHC; ICC; IP.
LAH522Hu71 Biotin-Linked Polyclonal Antibody to Nephronectin (NPNT) WB; IHC; ICC.
PAH522Hu02 Polyclonal Antibody to Nephronectin (NPNT) WB; IHC; ICC; IP.
PAH522Hu03 Polyclonal Antibody to Nephronectin (NPNT) WB; IHC; ICC; IP.
Assay Kits SEH522Hu ELISA Kit for Nephronectin (NPNT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH522Mu01 Recombinant Nephronectin (NPNT) Positive Control; Immunogen; SDS-PAGE; WB.
RPH522Mu02 Recombinant Nephronectin (NPNT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH522Mu01 Polyclonal Antibody to Nephronectin (NPNT) WB; IHC; ICC; IP.
PAH522Mu02 Polyclonal Antibody to Nephronectin (NPNT) WB; IHC; ICC; IP.
Assay Kits SEH522Mu ELISA Kit for Nephronectin (NPNT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH522Ra01 Recombinant Nephronectin (NPNT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nephronectin (NPNT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nephronectin (NPNT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nephronectin (NPNT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nephronectin (NPNT) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "Identification and characterization of a novel human nephronectin gene in silico."Int. J. Mol. Med. 15:719-724(2005) [PubMed] [Europe PMC] [Abstract]