-97506.jpg)
| CCC | H506 |
| HGNC | 8105 |
| PubMed | 22078758 |
| UniProt | P0CE72 |
| Wiki | Oncomodulin |
Oncomodulin and parvalbumin are structurally closely related, high-affinity calcium ion-binding proteins. Both belong to the superfamily of calmodulin proteins, also termed EF-hand proteins. Intron/exon organizations of the parvalbumin and oncomodulin genes are identical and the coding sequences are moderately similar, suggesting a common ancestor. Oncomodulin is a an oncodevelopmental protein found in early embryonic cells, in the placenta, and in tumors; parvalbumin is synthesized at highest levels in muscle fibers of the IIB type and in most GABAergic cells of the brain.
Analysis of human-mouse hybrids retaining portions of human chromosome 7 allowed specific assignment of the gene locus to 7p13-p11.the oncomodulin gene map to mouse chromosome 5.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH506Hu01 | Recombinant Oncomodulin (OCM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAH506Hu01 | Polyclonal Antibody to Oncomodulin (OCM) | WB |
| Assay Kits | n/a | CLIA Kit for Oncomodulin (OCM) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Oncomodulin (OCM) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH506Mu01 | Recombinant Oncomodulin (OCM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAH506Mu01 | Polyclonal Antibody to Oncomodulin (OCM) | IHC |
| Assay Kits | n/a | CLIA Kit for Oncomodulin (OCM) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Oncomodulin (OCM) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH506Ra01 | Recombinant Oncomodulin (OCM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAH506Ra01 | Polyclonal Antibody to Oncomodulin (OCM) | WB; IHC |
| Assay Kits | n/a | CLIA Kit for Oncomodulin (OCM) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Oncomodulin (OCM) | ELISA Kit Customized Service Offer |
- "Human alpha and beta parvalbumins. Structure and tissue-specific expression."Eur. J. Biochem. 215:719-727(1993) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of human beta-parvalbumin and structural comparison with its paralog alpha-parvalbumin and with their rat orthologs."Biochemistry 43:16076-16085(2004) [PubMed] [Europe PMC] [Abstract]