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Neurexin 3 (NRXN3)

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C14orf60

Neurexin 3 (NRXN3)
CCC F685
HGNC 8010
MGI 1096389
PubMed 19557197
UniProt Q9Y4C0
Wiki NRXN3
The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms; a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins.
NRXN3 is thought to be involved in synaptic plasticity, and polymorphisms in NRXN3 have been linked to genetic predisposition towards a number of conditions such as alcohol or drug addiction, or obesity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF685Hu01 Recombinant Neurexin 3 (NRXN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Neurexin 3 (NRXN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neurexin 3 (NRXN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neurexin 3 (NRXN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neurexin 3 (NRXN3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF685Mu01 Recombinant Neurexin 3 (NRXN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF685Mu01 Polyclonal Antibody to Neurexin 3 (NRXN3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Neurexin 3 (NRXN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neurexin 3 (NRXN3) ELISA Kit Customized Service Offer
  1. "Identification and characterization of heart-specific splicing of human neurexin 3 mRNA (NRXN3)."Biochem. Biophys. Res. Commun. 298:151-155(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity."Genomics 79:587-597(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions."Proc. Natl. Acad. Sci. U.S.A. 106:20782-20787(2009) [PubMed] [Europe PMC] [Abstract]