Annexin A4 (ANXA4)
[Edit]ANX-A4; ANX4; PIG28; 35-beta calcimedin; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; Lipocortin IV; Placental anticoagulant protein II
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Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways.
ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE784Mu01 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE784Mu02 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAE784Mu01 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB |
| PAE784Mu02 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB | |
| LAE784Mu71 | Biotin-Linked Polyclonal Antibody to Annexin A4 (ANXA4) | WB | |
| Assay Kits | n/a | CLIA Kit for Annexin A4 (ANXA4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Annexin A4 (ANXA4) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE784Ra01 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE784Ra02 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAE784Ra01 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; IHC |
| PAE784Ra02 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; IHC | |
| LAE784Ra71 | Biotin-Linked Polyclonal Antibody to Annexin A4 (ANXA4) | WB | |
| MAE784Ra21 | Monoclonal Antibody to Annexin A4 (ANXA4) | WB; IHC; ICC; IP. | |
| Assay Kits | n/a | CLIA Kit for Annexin A4 (ANXA4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Annexin A4 (ANXA4) | ELISA Kit Customized Service Offer |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE784Ca01 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE784Ca02 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAE784Ca01 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; ICC/IF |
| LAE784Ca71 | Biotin-Linked Polyclonal Antibody to Annexin A4 (ANXA4) | WB | |
| PAE784Ca02 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; ICC/IF | |
| Assay Kits | n/a | CLIA Kit for Annexin A4 (ANXA4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Annexin A4 (ANXA4) | ELISA Kit Customized Service Offer |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE784Po01 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE784Po02 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAE784Po01 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; IHC |
| PAE784Po02 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; IHC | |
| LAE784Po71 | Biotin-Linked Polyclonal Antibody to Annexin A4 (ANXA4) | WB | |
| MAE784Po21 | Monoclonal Antibody to Annexin A4 (ANXA4) | WB | |
| MAE784Po22 | Monoclonal Antibody to Annexin A4 (ANXA4) | WB | |
| MAE784Po23 | Monoclonal Antibody to Annexin A4 (ANXA4) | WB | |
| Assay Kits | n/a | CLIA Kit for Annexin A4 (ANXA4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Annexin A4 (ANXA4) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE784Bo01 | Recombinant Annexin A4 (ANXA4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAE784Bo01 | Polyclonal Antibody to Annexin A4 (ANXA4) | WB; IHC |
| Assay Kits | n/a | CLIA Kit for Annexin A4 (ANXA4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Annexin A4 (ANXA4) | ELISA Kit Customized Service Offer |
- "Isolation and expression of cDNA coding for a new member of the phospholipase A2 inhibitor family."Behring Inst. Mitt. 82:59-67(1988) [PubMed] [Europe PMC] [Abstract]
- "Chromosomal mapping of the human annexin IV (ANX4) gene."Genomics 12:313-318(1992) [PubMed] [Europe PMC] [Abstract]
- "Characterization of human p33/41 (annexin IV), a Ca2+ dependent carbohydrate-binding protein with monoclonal anti-annexin IV antibodies, AS11 and AS17."Biol. Pharm. Bull. 20:224-229(1997) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Placental anticoagulant proteins: isolation and comparative characterization four members of the lipocortin family."Biochemistry 27:6268-6276(1988) [PubMed] [Europe PMC] [Abstract]
- "Sedimentation equilibrium analysis of five lipocortin-related phospholipase A2 inhibitors from human placenta. Evidence against a mechanistically relevant association between enzyme and inhibitor."J. Biol. Chem. 263:18657-18663(1988) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
- "Crystallization and preliminary X-ray crystallographic studies of human placental annexin IV."J. Mol. Biol. 216:219-221(1990) [PubMed] [Europe PMC] [Abstract]