Lymphocyte Antigen 6E (LY6E)

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RIG-E; RIGE; SCA-2; SCA2; TSA-1; Retinoic Acid Induced Gene E; Stem cell antigen 2; Thymic shared antigen 1

Lymphocyte Antigen 6E (LY6E)
The deduced amino acid sequence predicts a cell surface protein containing 20 amino acids at the N-terminal end corresponding to a signal peptide and an extracellular sequence containing 111 amino acids.
The RIGE shares some homology with CD59 and with a number of growth factor receptors. It shares high sequence homology with the murine LY6 multigene family, whose members are small cysteine-rich proteins differentially expressed in several hematopoietic cell lines and with apparent function in signal transduction. RIGE is the closest human homolog of the LY6 family. They noted that expression of RIGE is not restricted to myeloid differentiation, because it is also present in thymocytes and in a number of other tissues at different levels.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE764Hu01 Recombinant Lymphocyte Antigen 6E (LY6E) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Lymphocyte Antigen 6E (LY6E) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lymphocyte Antigen 6E (LY6E) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lymphocyte Antigen 6E (LY6E) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphocyte Antigen 6E (LY6E) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE764Mu01 Recombinant Lymphocyte Antigen 6E (LY6E) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Lymphocyte Antigen 6E (LY6E) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lymphocyte Antigen 6E (LY6E) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lymphocyte Antigen 6E (LY6E) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphocyte Antigen 6E (LY6E) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE764Ra01 Recombinant Lymphocyte Antigen 6E (LY6E) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Lymphocyte Antigen 6E (LY6E) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lymphocyte Antigen 6E (LY6E) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lymphocyte Antigen 6E (LY6E) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphocyte Antigen 6E (LY6E) ELISA Kit Customized Service Offer
  1. "RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell."Proc. Natl. Acad. Sci. U.S.A. 93:5910-5914(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Identification through bioinformatics of cDNAs encoding human thymic shared Ag-1/stem cell Ag-2: a new member of the human Ly-6 family."J. Immunol. 157:969-973(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization and mapping to human chromosome 8q24.3 of Ly-6-related gene 9804 encoding an apparent homologue of mouse TSA-1."J. Immunol. 160:197-208(1998) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]