Sphingosine 1 Phosphate Receptor 3 (S1PR3)
[Edit]EDG3; LPB3; S1P3; S1PR3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; Sphingosine 1-phosphate receptor Edg-3
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Sphingosine-1-phosphate receptor 3 also known as S1PR3 is a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P3.
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.According to these guidelines, a receptor is to be named with the abbreviation of the natural agonist with the highest potency, followed by a subscripted arabic number. Thus they suggested that the designation EDG3 should be changed to S1P3.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE693Hu01 | Recombinant Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAE693Hu01 | Polyclonal Antibody to Sphingosine 1 Phosphate Receptor 3 (S1PR3) | WB; IHC; ICC; IP. |
| MAE693Hu21 | Monoclonal Antibody to Sphingosine 1 Phosphate Receptor 3 (S1PR3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEE693Hu | ELISA Kit for Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE693Mu01 | Recombinant Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE693Mu02 | Recombinant Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAE693Mu01 | Polyclonal Antibody to Sphingosine 1 Phosphate Receptor 3 (S1PR3) | WB; IHC; ICC; IP. |
| PAE693Mu02 | Polyclonal Antibody to Sphingosine 1 Phosphate Receptor 3 (S1PR3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEE693Mu | ELISA Kit for Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE693Ra01 | Recombinant Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAE693Ra01 | Polyclonal Antibody to Sphingosine 1 Phosphate Receptor 3 (S1PR3) | WB; IHC; ICC; IP. |
| MAE693Ra21 | Monoclonal Antibody to Sphingosine 1 Phosphate Receptor 3 (S1PR3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEE693Ra | ELISA Kit for Sphingosine 1 Phosphate Receptor 3 (S1PR3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9."Biochem. Biophys. Res. Commun. 227:608-614(1996) [PubMed] [Europe PMC] [Abstract]
- "Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids."FEBS Lett. 417:279-282(1997) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5."J. Biol. Chem. 274:18997-19002(1999) [PubMed] [Europe PMC] [Abstract]
- "Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5."J. Biol. Chem. 275:288-296(2000) [PubMed] [Europe PMC] [Abstract]
- "Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes."Mol. Pharmacol. 58:449-454(2000) [PubMed] [Europe PMC] [Abstract]