Regenerating Islet Derived Protein 3 Gamma (REG3g)

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REG-III; PAP1B; PAPIB; UNQ429; Pancreatitis-associated protein 1B; Regenerating islet-derived protein III-gamma

Regenerating Islet Derived Protein 3 Gamma (REG3g)
REG3G encodes a deduced 175-amino acid protein, with a predicted molecular mass of 16.5 kD after cleavage of a putative 26-amino acid N-terminal signal peptide. Two REG3G splice forms, with identical coding sequences but different 5-prime UTRs, were identified. The REG3G and REG3A proteins share 85% sequence homology. Northern blot analysis and RT-PCR experiments showed that REG3G is strongly expressed in pancreas, moderately in testis, and weakly in heart, kidney, and placenta. Further RT-PCR analysis of pancreas-derived cell lines showed that REG3G expression is limited to exocrine pancreas. Using 3-dimensional protein structural modeling, they showed that although REG3G and REG1A share similar structural features, they display distinctive surface charge distributions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE676Hu01 Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) Positive Control; Immunogen; SDS-PAGE; WB.
RPE676Hu02 Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE676Hu01 Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
MAE676Hu21 Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
PAE676Hu02 Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
MAE676Hu24 Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC
LAE676Hu76 Biotin-Linked Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC.
MAE676Hu26 Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB
MAE676Hu22 Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB
MAE676Hu23 Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
Assay Kits SEE676Hu ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE676Mu01 Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) Positive Control; Immunogen; SDS-PAGE; WB.
RPE676Mu02 Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE676Mu01 Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
LAE676Mu71 Biotin-Linked Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC.
LAE676Mu81 FITC-Linked Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IF.
PAE676Mu02 Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
Assay Kits SEE676Mu ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE676Ra01 Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE676Ra01 Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) WB; IHC; ICC; IP.
Assay Kits SEE676Ra ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III."Gene 340:161-170(2004) [PubMed] [Europe PMC] [Abstract]
  2. "PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication."Biochim. Biophys. Acta 1727:177-187(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment."J. Biol. Chem. 284:4881-4888(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]