Solute Carrier Family 3, Member 2 (SLC3A2)
[Edit]SLC3A2; CD98HC; 4F2; 4F2HC; 4T2HC; MDU1; NACAE; Activators Of Dibasic And Neutral Amino Acid Transport; Antigen Identified By Monoclonal Antibodies 4F2; CD98 Heavy Chain
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SLC3A2 is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha-amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. It associates with integrins and mediates integrin-dependent signaling related to normal cell growth and tumorigenesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta was significantly stronger at full-term than at the mid- trimester stage.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE348Hu01 | Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE348Hu02 | Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAE348Hu01 | Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC; IP. |
| PAE348Hu02 | Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC; IP. | |
| LAE348Hu71 | Biotin-Linked Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC. | |
| Assay Kits | SEE348Hu | ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE348Mu01 | Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAE348Mu01 | Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC; IP. |
| LAE348Mu81 | FITC-Linked Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC; IF. | |
| LAE348Mu71 | Biotin-Linked Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC. | |
| Assay Kits | n/a | CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE348Ra01 | Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAE348Ra01 | Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) | ELISA Kit Customized Service Offer |
- "Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth."Proc. Natl. Acad. Sci. U.S.A. 84:6526-6530(1987) [PubMed] [Europe PMC] [Abstract]
- ErratumProc. Natl. Acad. Sci. U.S.A. 84:8618-8618(1987)
- "Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus."J. Biol. Chem. 262:9574-9580(1987) [PubMed] [Europe PMC] [Abstract]
- "Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2."Proc. Natl. Acad. Sci. U.S.A. 84:9204-9208(1987) [PubMed] [Europe PMC] [Abstract]
- "Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation."Mol. Cell. Biol. 8:3809-3819(1988) [PubMed] [Europe PMC] [Abstract]
- "Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines."Biochim. Biophys. Acta 1514:291-302(2001) [PubMed] [Europe PMC] [Abstract]
- "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]