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Elastase 3B (ELA3B)

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CELA3B; Chymotrypsin Like Elastase Family Member 3B; Protease E; Fecal Elastase; Elastase 1; Cholesterol-Binding Pancreatic Protease; Pancreatic Endopeptidase E

Elastase 3B (ELA3B)
CCC E212
HGNC 15945
MGI 1915118
PubMed 20428826
RGD 1307819
UniProt P08861
Wiki ELA3B
Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays..

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE212Hu01 Recombinant Elastase 3B (ELA3B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE212Hu01 Polyclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC; IP.
LAE212Hu71 Biotin-Linked Polyclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC.
MAE212Hu21 Monoclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC; IP.
Assay Kits SEE212Hu ELISA Kit for Elastase 3B (ELA3B) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE212Mu01 Recombinant Elastase 3B (ELA3B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE212Mu01 Polyclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC; IP.
LAE212Mu71 Biotin-Linked Polyclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Elastase 3B (ELA3B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Elastase 3B (ELA3B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE212Ra01 Recombinant Elastase 3B (ELA3B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE212Ra01 Polyclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC; IP.
LAE212Ra71 Biotin-Linked Polyclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC.
MAE212Ra21 Monoclonal Antibody to Elastase 3B (ELA3B) WB; IHC; ICC; IP.
Assay Kits SEE212Ra ELISA Kit for Elastase 3B (ELA3B) Enzyme-linked immunosorbent assay for Antigen Detection.
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  10. "Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism."J. Invest. Dermatol. 114:165-170(2000) [PubMed] [Europe PMC] [Abstract]