Tropomyosin 3 (TPM3)

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NEM1; TRK; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TPMsk3; Hscp30; Gamma-tropomyosin

Tropomyosin 3 (TPM3)
Tropomyosin alpha-3 chain is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD449Hu01 Recombinant Tropomyosin 3 (TPM3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD449Hu01 Polyclonal Antibody to Tropomyosin 3 (TPM3) WB; IHC; ICC; IP.
MAD449Hu21 Monoclonal Antibody to Tropomyosin 3 (TPM3) WB; IHC; ICC; IP.
Assay Kits SED449Hu ELISA Kit for Tropomyosin 3 (TPM3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD449Mu01 Recombinant Tropomyosin 3 (TPM3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD449Mu01 Polyclonal Antibody to Tropomyosin 3 (TPM3) WB; IHC; ICC; IP.
Assay Kits SED449Mu ELISA Kit for Tropomyosin 3 (TPM3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD449Ra01 Recombinant Tropomyosin 3 (TPM3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Tropomyosin 3 (TPM3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tropomyosin 3 (TPM3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tropomyosin 3 (TPM3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tropomyosin 3 (TPM3) ELISA Kit Customized Service Offer
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  7. , Submitted (DEC-2005) to UniProtKB
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