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Dickkopf Related Protein 3 (DKK3)

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REIC

Dickkopf Related Protein 3 (DKK3)
CCC D410
HGNC 2893
MGI 1354952
PubMed 22918120
RGD 621846
UniProt Q9UBP4
Wiki DKK3
DKK3 is a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.DKK3 has 4 potential N-glycosylation sites and possesses an extended N-terminal domain preceding the first cys domain as well as an extended C-terminal region following the second cys domain. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of a 2.5-kb DKK3 transcript, with highest expression in heart, brain, and spinal cord.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD410Hu01 Recombinant Dickkopf Related Protein 3 (DKK3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD410Hu01 Polyclonal Antibody to Dickkopf Related Protein 3 (DKK3) WB; ICC; IHC-P; IHC-F; ELISA.
Assay Kits SED410Hu ELISA Kit for Dickkopf Related Protein 3 (DKK3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD410Mu01 Recombinant Dickkopf Related Protein 3 (DKK3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD410Mu01 Polyclonal Antibody to Dickkopf Related Protein 3 (DKK3) WB; IHC; ICC; IP.
Assay Kits SED410Mu ELISA Kit for Dickkopf Related Protein 3 (DKK3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD410Ra01 Recombinant Dickkopf Related Protein 3 (DKK3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD410Ra01 Polyclonal Antibody to Dickkopf Related Protein 3 (DKK3) WB; IHC; ICC; IP.
MAD410Ra21 Monoclonal Antibody to Dickkopf Related Protein 3 (DKK3) WB; IHC; ICC; IP.
Assay Kits SED410Ra ELISA Kit for Dickkopf Related Protein 3 (DKK3) Enzyme-linked immunosorbent assay for Antigen Detection.
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