Slit Homolog 3 (Slit3)

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MEGF5; SLIL2; Multiple epidermal growth factor-like domains protein 5

Slit Homolog 3 (Slit3)
The SLIT3 cDNA encodes a 1,523-amino acid polypeptide with 41.1% similarity to the Drosophila 'slit' protein. Northern blot analysis revealed that the human SLIT3 gene was expressed as a major 5.5- and a minor 9.5-kb transcript primarily in the thyroid. SLIT1 and SLIT2 mRNAs were primarily expressed in the brain and spinal cord, respectively. In situ hybridization studies indicated that the rat Slit1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. These data suggested that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD353Hu01 Recombinant Slit Homolog 3 (Slit3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD353Hu01 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC
LAD353Hu71 Biotin-Linked Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC.
LAD353Hu81 FITC-Linked Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IF.
MAD353Hu21 Monoclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
Assay Kits SED353Mi ELISA Kit for Slit Homolog 3 (Slit3) Enzyme-linked immunosorbent assay for Antigen Detection.
SED353Hu ELISA Kit for Slit Homolog 3 (Slit3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD353Mu01 Recombinant Slit Homolog 3 (Slit3) Positive Control; Immunogen; SDS-PAGE; WB.
RPD353Mu02 Recombinant Slit Homolog 3 (Slit3) Positive Control; Immunogen; SDS-PAGE; WB.
RPD353Mu03 Recombinant Slit Homolog 3 (Slit3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD353Mu01 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
PAD353Mu02 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
PAD353Mu03 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
LAD353Mu71 Biotin-Linked Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC.
LAD353Mu81 FITC-Linked Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IF.
Assay Kits SED353Mi ELISA Kit for Slit Homolog 3 (Slit3) Enzyme-linked immunosorbent assay for Antigen Detection.
SED353Mu ELISA Kit for Slit Homolog 3 (Slit3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD353Ra01 Recombinant Slit Homolog 3 (Slit3) Positive Control; Immunogen; SDS-PAGE; WB.
RPD353Ra02 Recombinant Slit Homolog 3 (Slit3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD353Ra01 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
PAD353Ra02 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
LAD353Ra71 Biotin-Linked Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC.
LAD353Ra81 FITC-Linked Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IF.
MAD353Ra21 Monoclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
MAD353Ra22 Monoclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
PAD353Ra03 Polyclonal Antibody to Slit Homolog 3 (Slit3) WB; IHC; ICC; IP.
Assay Kits SED353Mi ELISA Kit for Slit Homolog 3 (Slit3) Enzyme-linked immunosorbent assay for Antigen Detection.
SED353Ra ELISA Kit for Slit Homolog 3 (Slit3) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system."Brain Res. Mol. Brain Res. 62:175-186(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening."Genomics 51:27-34(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis."Mech. Dev. 79:57-72(1998) [PubMed] [Europe PMC] [Abstract]