Thyroid Stimulating Hormone Beta (TSHb)

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TSH-B; Thyrotropin beta chain; Thyrotropin alfa

Thyroid Stimulating Hormone Beta (TSHb)
Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit (TSHA) and a unique beta subunit that confers specificity.Using bovine TSHB cDNA as probe, Hayashizaki et al. (1985) cloned TSHB from human liver and leukocyte genomic DNA libraries. Human TSHB encodes a deduced protein consisting of a 20-amino acid signal sequence, a mature protein of 112 amino acids, and a C-terminal extension of 6 hydrophobic amino acids. Wondisford et al. (1988) also cloned the human TSHB gene.Wondisford et al. (1988) determined that the TSHB gene contains 3 exons, the first of which is noncoding. The rat TSHB gene also contains one 5-prime noncoding exon, whereas the mouse Tshb gene contains 3.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD213Hu01 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
RPD213Hu02 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD213Hu01 Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD213Mu01 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD213Mu01 Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC; IP.
LAD213Mu71 Biotin-Linked Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC.
LAD213Mu81 FITC-Linked Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC; IF.
MAD213Mu21 Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD213Ra01 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD213Ra01 Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD213Ca01 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD213Ca01 Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB
Assay Kits n/a CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD213Ga01 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD213Ga01 Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC; IP.
LAD213Ga71 Biotin-Linked Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) ELISA Kit Customized Service Offer

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD213Fi01 Recombinant Thyroid Stimulating Hormone Beta (TSHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) ELISA Kit Customized Service Offer
  1. "Molecular cloning of the human thyrotropin-beta subunit gene."FEBS Lett. 188:394-400(1985) [PubMed] [Europe PMC] [Abstract]
  2. "The human thyrotropin beta-subunit gene differs in 5' structure from murine TSH-beta genes."DNA 7:691-699(1988) [PubMed] [Europe PMC] [Abstract]
  3. "The structure of the human thyrotropin beta-subunit gene."Gene 73:489-497(1988) [PubMed] [Europe PMC] [Abstract]
  4. "Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species."J. Biol. Chem. 263:12538-12542(1988) [PubMed] [Europe PMC] [Abstract]
  5. "Structure and regulation of human thyroid-stimulating hormone (TSH) gene."Nippon Rinsho 52:940-947(1994) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "A novel thyroid stimulating hormone beta-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid."Gen. Comp. Endocrinol. 162:241-244(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Human pituitary thyrotropin. The primary structure of the alpha and beta subunits."Can. J. Biochem. 55:755-760(1977) [PubMed] [Europe PMC] [Abstract]