Fibroblast Growth Factor 13 (FGF13)

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FHF2; Fibroblast Growth Factor Homologous Factor 2

Fibroblast Growth Factor 13 (FGF13)
Fibroblast growth factor 13 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC915Hu01 Recombinant Fibroblast Growth Factor 13 (FGF13) Positive Control; Immunogen; SDS-PAGE; WB.
RPC915Hu02 Recombinant Fibroblast Growth Factor 13 (FGF13) Positive Control; Immunogen; SDS-PAGE; WB.
CPC915Hu21 OVA Conjugated Fibroblast Growth Factor 13 (FGF13) Immunogen; SDS-PAGE; WB.
APC915Hu01 Active Fibroblast Growth Factor 13 (FGF13) Cell culture; Activity Assays.
APC915Hu02 Active Fibroblast Growth Factor 13 (FGF13) Cell culture; Activity Assays.
Antibodies PAC915Hu01 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
PAC915Hu02 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
LAC915Hu71 Biotin-Linked Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC.
LAC915Hu81 FITC-Linked Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IF.
MAC915Hu21 Monoclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC
PAC915Hu08 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
MAC915Hu22 Monoclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
MAC915Hu23 Monoclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
Assay Kits CEC915Hu ELISA Kit for Fibroblast Growth Factor 13 (FGF13) Enzyme-linked immunosorbent assay for Antigen Detection.
CCC915Hu CLIA Kit for Fibroblast Growth Factor 13 (FGF13) Chemiluminescent immunoassay for Antigen Detection.
HEC915Hu High Sensitive ELISA Kit for Fibroblast Growth Factor 13 (FGF13) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC915Hu CLIA Kit for Fibroblast Growth Factor 13 (FGF13) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC915Mu01 Recombinant Fibroblast Growth Factor 13 (FGF13) Positive Control; Immunogen; SDS-PAGE; WB.
RPC915Mu02 Recombinant Fibroblast Growth Factor 13 (FGF13) Positive Control; Immunogen; SDS-PAGE; WB.
CPC915Mu21 OVA Conjugated Fibroblast Growth Factor 13 (FGF13) Immunogen; SDS-PAGE; WB.
Antibodies PAC915Mu01 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
PAC915Mu02 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
PAC915Mu08 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
Assay Kits SEC915Mu ELISA Kit for Fibroblast Growth Factor 13 (FGF13) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC915Mu CLIA Kit for Fibroblast Growth Factor 13 (FGF13) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC915Ra01 Recombinant Fibroblast Growth Factor 13 (FGF13) Positive Control; Immunogen; SDS-PAGE; WB.
CPC915Ra21 OVA Conjugated Fibroblast Growth Factor 13 (FGF13) Immunogen; SDS-PAGE; WB.
APC915Ra01 Active Fibroblast Growth Factor 13 (FGF13) Cell culture; Activity Assays.
Antibodies PAC915Ra01 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
MAC915Ra21 Monoclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
PAC915Ra08 Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) WB; IHC; ICC; IP.
Assay Kits SEC915Ra ELISA Kit for Fibroblast Growth Factor 13 (FGF13) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC915Ra CLIA Kit for Fibroblast Growth Factor 13 (FGF13) Chemiluminescent immunoassay for Antigen Detection.
  1. "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development."Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Fibroblast growth factor homologous factor 2 (FHF2): gene structure, expression and mapping to the Borjeson-Forssman-Lehmann syndrome region in Xq26 delineated by a duplication breakpoint in a BFLS-like patient."Hum. Genet. 104:56-63(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Isoform diversity among fibroblast growth factor homologous factors is generated by alternative promoter usage and differential splicing."J. Biol. Chem. 275:2589-2597(2000) [PubMed] [Europe PMC] [Abstract]
  7. "Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart."Mech. Dev. 64:31-39(1997) [PubMed] [Europe PMC] [Abstract]
  8. "Fibroblast growth factor homologous factors are intracellular signaling proteins."Curr. Biol. 11:793-797(2001) [PubMed] [Europe PMC] [Abstract]
  9. "Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons."J. Neurosci. 24:6765-6775(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts."Circ. Res. 109:775-782(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels."J. Biol. Chem. 286:24253-24263(2011) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels."J. Biol. Chem. 284:17883-17896(2009) [PubMed] [Europe PMC] [Abstract]