YY1 Associated Factor 2 (YAF2)
YY1-associated factor 2 is a protein interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
YAF2 mRNA increased during the in vitro differentiation of rat skeletal and cardiac muscle cells, in contrast to the downregulation of YY1. Overexpression of YAF2 in mouse myoblast cells stimulated myogenic promoter activity. Cotransfection and expression of YY1 in these cells reversed the stimulatory effect of YAF2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC610Hu01 Recombinant YY1 Associated Factor 2 (YAF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC610Hu01 Polyclonal Antibody to YY1 Associated Factor 2 (YAF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for YY1 Associated Factor 2 (YAF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for YY1 Associated Factor 2 (YAF2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC610Mu01 Recombinant YY1 Associated Factor 2 (YAF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC610Mu01 Polyclonal Antibody to YY1 Associated Factor 2 (YAF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for YY1 Associated Factor 2 (YAF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for YY1 Associated Factor 2 (YAF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC610Ra01 Recombinant YY1 Associated Factor 2 (YAF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC610Ra01 Polyclonal Antibody to YY1 Associated Factor 2 (YAF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for YY1 Associated Factor 2 (YAF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for YY1 Associated Factor 2 (YAF2) ELISA Kit Customized Service Offer
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