Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB)

[Edit]

QP-C; QPC; UQBC; UQBP; UQPC; Ubiquinol-Cytochrome C Reductase,Complex III Subunit VI; Ubiquinol-cytochrome c reductase complex 14 kDa protein

Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB)
UQCRB is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR,Complex III or Cytochrome bc1 complex), Subunit 7 was identified as a Q-binding protein by photo-labeling with a ubiquinone analog (subsequent structures show it to be exposed to the lipid phase but not involved in either Q-binding site). Subunits 6 and 7 reverse position on going from Laemli gels to Weber&Osborne gels, and one might suspect the name "Q-binding protein" arose from confusion with subunit 7. I have been told however that this is not the case, and both proteins were separately identified as Q-binding proteins. Genome anotators improved the situation by naming its gene "UQCR binding", UQCRB.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC589Hu01 Recombinant Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC589Hu01 Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC589Mu01 Recombinant Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC589Mu01 Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC589Ra01 Recombinant Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC589Ra01 Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ubiquinol Cytochrome C Reductase Binding Protein (UQCRB) ELISA Kit Customized Service Offer
  1. "Cloning and sequencing of a cDNA for human mitochondrial ubiquinone-binding protein of complex III."Biochem. Biophys. Res. Commun. 156:987-994(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation of a single nuclear gene encoding human ubiquinone-binding protein in complex III of mitochondrial respiratory chain."Biochem. Biophys. Res. Commun. 161:371-378(1989) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Common protein-binding sites in the 5'-flanking regions of human genes for cytochrome c1 and ubiquinone-binding protein."J. Biol. Chem. 265:8159-8163(1990) [PubMed] [Europe PMC] [Abstract]
  6. "A deletion in the human QP-C gene causes a complex III deficiency resulting in hypoglycaemia and lactic acidosis."Hum. Genet. 113:118-122(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]