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Glycophorin E (GYPE)

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GYP-E; MNS; GPE; MiIX

Glycophorin E (GYPE)
CCC C504
HGNC 4705
PubMed 2295603
UniProt P15421
Wiki GYPE
A Glycophorin is a sialoglycoprotein of the membrane of a red blood cell. It is a membrane-spanning protein and carries sugar molecules. It is heavily glycosylated (60%). Glycophorins are rich in sialic acid, which gives the red cells a very hydrophilic-charged coat. This enables them to circulate without adhering to other cells or vessel walls.
Glycophorin-E is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC504Hu01 Recombinant Glycophorin E (GYPE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC504Hu01 Polyclonal Antibody to Glycophorin E (GYPE) WB
Assay Kits n/a CLIA Kit for Glycophorin E (GYPE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycophorin E (GYPE) ELISA Kit Customized Service Offer
  1. "Identification of a novel human glycophorin, glycophorin E, by isolation of genomic clones and complementary DNA clones utilizing polymerase chain reaction."J. Biol. Chem. 265:1102-1110(1990) [PubMed] [Europe PMC] [Abstract]
  2. "A novel gene member of the human glycophorin A and B gene family. Molecular cloning and expression."Eur. J. Biochem. 191:619-625(1990) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Promoter sequence and chromosomal organization of the genes encoding glycophorins A, B and E."Gene 95:289-293(1990) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of glycophorin A transcripts: control by the common erythroid-specific promoter and alternative usage of different polyadenylation signals."J. Biochem. 116:183-192(1994) [PubMed] [Europe PMC] [Abstract]