Frataxin (FXN)
[Edit]FA; CyaY; FARR; FRDA; X25; Friedreich ataxia protein; Frataxin intermediate form; Frataxin, mitochondrial
![Frataxin (FXN)](/upload/item/img/Frataxin-(FXN)-92493.jpg)
Frataxin is a small protein, localized to the mitochondrion. The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron Chaperone (protein) or an iron storage protein.Reduced expression of frataxin is the cause of Friedrich's ataxia (FRDA), a lethal neurodegenerative disease.
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC493Hu01 | Recombinant Frataxin (FXN) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC493Hu01 | Polyclonal Antibody to Frataxin (FXN) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Frataxin (FXN) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Frataxin (FXN) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC493Mu01 | Recombinant Frataxin (FXN) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC493Mu02 | Recombinant Frataxin (FXN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC493Mu01 | Polyclonal Antibody to Frataxin (FXN) | WB; IHC; ICC; IP. |
PAC493Mu02 | Polyclonal Antibody to Frataxin (FXN) | WB; IHC; ICC; IP. | |
Assay Kits | SEC493Mu | ELISA Kit for Frataxin (FXN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC493Ra01 | Recombinant Frataxin (FXN) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Frataxin (FXN) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Frataxin (FXN) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Frataxin (FXN) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Frataxin (FXN) | ELISA Kit Customized Service Offer |
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