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Macrophage Inflammatory Protein 1 Gamma (MIP1g)

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CCL9; CCL10; SCYB9; CCF18; MRP2; C-C motif chemokine 9; Macrophage inflammatory protein-related protein 2; Small-inducible cytokine A9

Macrophage Inflammatory Protein 1 Gamma (MIP1g)
CCC C073
MGI 104533
PubMed 22810435
RGD 1310563
UniProt P51670
Wiki CCL9

Chemokine (C-C motif) ligand 9 (CCL9) is a small cytokine belonging to the CC chemokine family. It is also called macrophage inflammatory protein-1 gamma (MIP-1γ), macrophage inflammatory protein-related protein-2 (MRP-2) and CCF18 , that has been described in rodents. CCL9 has also been previously designated CCL10, although this name is no longer in use. It is secreted by follicle-associated epithelium (FAE) such as that found around Peyer's patches, and attracts dendritic cells that possess the cell surface molecule CD11b and the chemokine receptor CCR1.

CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption. CCL9 is constitutively expressed in macrophages and myeloid cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins APC073Hu01 Active Macrophage Inflammatory Protein 1 Gamma (MIP1g) Cell culture; Activity Assays.
Antibodies n/a Monoclonal Antibody to Macrophage Inflammatory Protein 1 Gamma (MIP1g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Macrophage Inflammatory Protein 1 Gamma (MIP1g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Macrophage Inflammatory Protein 1 Gamma (MIP1g) CLIA Kit Customized Service Offer
n/a ELISA Kit for Macrophage Inflammatory Protein 1 Gamma (MIP1g) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC073Mu01 Recombinant Macrophage Inflammatory Protein 1 Gamma (MIP1g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC073Mu01 Polyclonal Antibody to Macrophage Inflammatory Protein 1 Gamma (MIP1g) WB; IHC; ICC; IP.
Assay Kits SEC073Mu ELISA Kit for Macrophage Inflammatory Protein 1 Gamma (MIP1g) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC073Ra01 Recombinant Macrophage Inflammatory Protein 1 Gamma (MIP1g) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC073Ra01 Polyclonal Antibody to Macrophage Inflammatory Protein 1 Gamma (MIP1g) WB; IHC; ICC; IP.
LAC073Ra81 FITC-Linked Polyclonal Antibody to Macrophage Inflammatory Protein 1 Gamma (MIP1g) WB; IHC; ICC; IF.
Assay Kits SEC073Ra ELISA Kit for Macrophage Inflammatory Protein 1 Gamma (MIP1g) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "MIP-1 gamma: molecular cloning, expression, and biological activities of a novel CC chemokine that is constitutively secreted in vivo."J. Inflamm. 45:207-219(1995) [PubMed] [Europe PMC] [Abstract]
  2. "A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors."J. Immunol. 155:2661-2667(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular cloning and functional characterization of a novel member of the C-C chemokine family."J. Immunol. 155:5352-5358(1995) [PubMed] [Europe PMC] [Abstract]
  4. "Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis."J. Immunol. 163:2262-2266(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Lineage-specific biology revealed by a finished genome assembly of the mouse." PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Proteolytic activation of alternative CCR1 ligands in inflammation."J. Immunol. 174:7341-7351(2005) [PubMed] [Europe PMC] [Abstract]