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Farnesoid X Receptor (FXR)

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NR1H4; BAR; FXR; HRR1; RIP14; Nuclear Receptor Subfamily 1,Group H,Member 4; Bile acid receptor; Farnesol receptor HRR-1; Retinoid X receptor-interacting protein 14

Farnesoid X Receptor (FXR)
CCC C042
HGNC 7967
MGI 1352464
PubMed 22648540
RGD 628831
UniProt Q96RI1
Wiki FXR

The farnesoid X receptor (FXR),is a nuclear hormone receptor with activity similar to that seen in other steroid receptors such as estrogen or progesterone but more similar in form to PPAR, LXR and RXR. FXR is encoded by the NR1H4 gene.

FXR is expressed at high levels in the liver and intestine. Chenodeoxycholic acid and other bile acids are natural ligands for FXR. Like other steroid receptors, when activated, FXR translocates to the cell nucleus, forms a dimer (in this case a heterodimer with RXR) and binds to hormone response elements on DNA which elicits expression or transrepression of gene products.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC042Hu01 Recombinant Farnesoid X Receptor (FXR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC042Hu01 Polyclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
MAC042Hu22 Monoclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
Assay Kits SEC042Hu ELISA Kit for Farnesoid X Receptor (FXR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC042Mu01 Recombinant Farnesoid X Receptor (FXR) Positive Control; Immunogen; SDS-PAGE; WB.
RPC042Mu02 Recombinant Farnesoid X Receptor (FXR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC042Mu01 Polyclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
PAC042Mu02 Polyclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
Assay Kits SEC042Mu ELISA Kit for Farnesoid X Receptor (FXR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC042Ra01 Recombinant Farnesoid X Receptor (FXR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC042Ra01 Polyclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
MAC042Ra21 Monoclonal Antibody to Farnesoid X Receptor (FXR) WB; IHC; ICC; IP.
Assay Kits SEC042Ra ELISA Kit for Farnesoid X Receptor (FXR) Enzyme-linked immunosorbent assay for Antigen Detection.
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