![Inositol Triphosphate (IP3)](/upload/item/img/Inositol-Triphosphate-(IP3)-92037.jpg)
CCC | C037 |
CAS | 85166-31-0 |
Wiki | IP3 |
Inositol trisphosphate is a secondary messenger molecule used in signal transduction in biological cells. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the plasma membrane, by phospholipase C. IP3 binds to and activates the InsP3 receptor on the membrane of the endoplasmic reticulum (ER), and sarcoplasmic reticulum (SR) opens a calcium channel, resulting in the release of Ca2 into the cytoplasm, and sarcoplasm respectively. This increase in Ca2 activates the ryanodine receptor-operated channel on the SR, leading to a further increase in the Ca2 .
Its main functions are to mobilize Ca2+ from storage organelles and to regulate cell proliferation and other cellular reactions.In smooth muscle cells, for example, the increase in concentration of cytoplasmic calcium results in the contraction of the muscle cell.
Organism species: Pan-species (General)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Complete Antigen of Inositol Triphosphate (IP3) | Antigenic Transformation Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Inositol Triphosphate (IP3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Inositol Triphosphate (IP3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | CEC037Ge | ELISA Kit for Inositol Triphosphate (IP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CCC037Ge | CLIA Kit for Inositol Triphosphate (IP3) | Chemiluminescent immunoassay for Antigen Detection. |