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Interleukin-29 (IL-29) is a protein of the helical cytokine family and is a type III interferon. It is also known as IFN lambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon.
IL-29 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC029Hu01 | Recombinant Interleukin 29 (IL29) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APC029Hu01 | Active Interleukin 29 (IL29) | Cell culture; Activity Assays. | |
| EPC029Hu61 | Eukaryotic Interleukin 29 (IL29) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAC029Hu01 | Polyclonal Antibody to Interleukin 29 (IL29) | WB; IHC; ICC; IP. |
| MAC029Hu22 | Monoclonal Antibody to Interleukin 29 (IL29) | WB,IHC | |
| MAC029Hu21 | Monoclonal Antibody to Interleukin 29 (IL29) | WB; IHC; ICC; IP. | |
| MAC029Hu23 | Monoclonal Antibody to Interleukin 29 (IL29) | WB; IHC; ICC; IP. | |
| MAC029Hu24 | Monoclonal Antibody to Interleukin 29 (IL29) | WB; IHC; ICC; IP. | |
| MAC029Hu25 | Monoclonal Antibody to Interleukin 29 (IL29) | WB; IHC; ICC; IP. | |
| MAC029Hu27 | Monoclonal Antibody to Interleukin 29 (IL29) | WB; IHC; ICC; IP. | |
| Assay Kits | SEC029Hu | ELISA Kit for Interleukin 29 (IL29) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCC029Hu | CLIA Kit for Interleukin 29 (IL29) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Interleukin 29 (IL29) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 29 (IL29) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 29 (IL29) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Interleukin 29 (IL29) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 29 (IL29) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC029Ra01 | Recombinant Interleukin 29 (IL29) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPC029Ra61 | Eukaryotic Interleukin 29 (IL29) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APC029Ra61 | Active Interleukin 29 (IL29) | Cell culture; Activity Assays. | |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 29 (IL29) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 29 (IL29) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Interleukin 29 (IL29) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 29 (IL29) | ELISA Kit Customized Service Offer |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC029Po01 | Recombinant Interleukin 29 (IL29) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Interleukin 29 (IL29) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Interleukin 29 (IL29) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Interleukin 29 (IL29) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 29 (IL29) | ELISA Kit Customized Service Offer |
- "IL-28, IL-29 and their class II cytokine receptor IL-28R." Nat. Immunol. 4:63-68(2003) [PubMed] [Europe PMC] [Abstract]
- "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex."Nat. Immunol. 4:69-77(2003) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Interferon-lambda: a new addition to an old family."J. Interferon Cytokine Res. 30:555-564(2010) [PubMed] [Europe PMC] [Abstract]
- "Interferon-lambda in the context of viral infections: production, response and therapeutic implications."J. Innate Immun. 6:563-574(2014) [PubMed] [Europe PMC] [Abstract]
- "Crystal structure of human interferon-lambda1 in complex with its high-affinity receptor interferon-lambdaR1."J. Mol. Biol. 404:650-664(2010) [PubMed] [Europe PMC] [Abstract]