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Toll Like Receptor 1 (TLR1)

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CD281; TIL; Rsc786; Toll/interleukin-1 receptor-like protein

Toll Like Receptor 1 (TLR1)
CCC B988
HGNC 11847
MGI 1341295
PubMed 21618349
UniProt Q15399
Wiki TLR_1

TLR 1 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. TLR1 recognizes pathogen-associated molecular pattern with a specificity for gram-positive bacteria. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB988Hu01 Recombinant Toll Like Receptor 1 (TLR1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB988Hu02 Recombinant Toll Like Receptor 1 (TLR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB988Hu01 Polyclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
MAB988Hu22 Monoclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
PAB988Hu02 Polyclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
LAB988Hu71 Biotin-Linked Polyclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC.
LAB988Hu81 FITC-Linked Polyclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IF.
MAB988Hu21 Monoclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
MAB988Hu23 Monoclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
Assay Kits SEB988Hu ELISA Kit for Toll Like Receptor 1 (TLR1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB988Mu01 Recombinant Toll Like Receptor 1 (TLR1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB988Mu02 Recombinant Toll Like Receptor 1 (TLR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB988Mu01 Polyclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
PAB988Mu02 Polyclonal Antibody to Toll Like Receptor 1 (TLR1) WB; IHC; ICC; IP.
Assay Kits SEB988Mu ELISA Kit for Toll Like Receptor 1 (TLR1) Enzyme-linked immunosorbent assay for Antigen Detection.
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  13. "Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family."Hum. Mutat. 32:643-652(2011) [PubMed] [Europe PMC] [Abstract]