Allopregnanolone (AP)

Allopregnanolone, also known as 3α,5α-tetrahydroprogesterone or THP, is an important neurosteroid in the human brain. It is a metabolite of progesterone and a barbiturate-like modulator of central gamma-aminobutyric acid (GABA) receptors that modify a range of behaviors, including the stress response.

The 5β epimer of this compound is known as pregnanolone, and has very similar properties to allopregnanolone. Both compounds are found endogenously and have similar hypnotic and anxiolytic effects.

The production of allopregnanolone starts with 5-alpha-reductase converting progesterone into pregnanolone. After that, 3beta-hydroxy-5alpha-steroid dehydrogenase converts the former into allopregnanolone.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPB963Ge11 BSA Conjugated Allopregnanolone (AP) Immunogen; SDS-PAGE; WB.
CPB963Ge21 OVA Conjugated Allopregnanolone (AP) Immunogen; SDS-PAGE; WB.
Antibodies PAB963Ge01 Polyclonal Antibody to Allopregnanolone (AP) WB; IHC; ICC; IP.
MAB963Ge21 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAB963Ge22 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAB963Ge24 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAB963Ge27 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAB963Ge23 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAB963Ge25 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
MAB963Ge28 Monoclonal Antibody to Allopregnanolone (AP) ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
Assay Kits CEB963Ge ELISA Kit for Allopregnanolone (AP) Enzyme-linked immunosorbent assay for Antigen Detection.