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Ficolin 2 (FCN2)

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EBP37; FCNL; P35; Hucolin; 37 kDa elastin-binding protein; Collagen/Fibrinogen Domain Containing Lectin; Ficolin B; Serum Lectin p35; L-Ficolin

Ficolin 2 (FCN2)
CCC B907
HGNC 3624
PubMed 23298162
UniProt Q15485
Wiki FCN2

Ficolin-2 belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified.

Serum concentration of ficolin-2 varies considerably in healthy individuals.FCN2 promoter polymorphisms were associated with marked changes in the ficolin-2 serum concentration, whereas 2 nonsynonymous SNPs clustered in exon 8 encoding the fibrinogen-like domain were associated with decreased and increased GlcNAc binding, respectively.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB907Hu01 Recombinant Ficolin 2 (FCN2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB907Hu01 Polyclonal Antibody to Ficolin 2 (FCN2) WB; IHC; ICC; IP.
MAB907Hu22 Monoclonal Antibody to Ficolin 2 (FCN2) WB; IHC; ICC; IP.
Assay Kits SEB907Hu ELISA Kit for Ficolin 2 (FCN2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB907Mu01 Recombinant Ficolin 2 (FCN2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB907Mu01 Polyclonal Antibody to Ficolin 2 (FCN2) WB; IHC; ICC; IP.
Assay Kits SEB907Mu ELISA Kit for Ficolin 2 (FCN2) Enzyme-linked immunosorbent assay for Antigen Detection.
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