Cluster Of Differentiation (CD163)
[Edit]M130; MM130; Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor
CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages.Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin c by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage.
CD163 may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. It exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB726Hu01 | Recombinant Cluster Of Differentiation (CD163) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB726Hu01 | Polyclonal Antibody to Cluster Of Differentiation (CD163) | WB; IHC; ICC; IP. |
MAB726Hu21 | Monoclonal Antibody to Cluster Of Differentiation (CD163) | WB; IHC; ICC; IP. | |
Assay Kits | SEB726Hu | ELISA Kit for Cluster Of Differentiation (CD163) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB726Mu01 | Recombinant Cluster Of Differentiation (CD163) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB726Mu02 | Recombinant Cluster Of Differentiation (CD163) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB726Mu01 | Polyclonal Antibody to Cluster Of Differentiation (CD163) | WB; IHC; ICC; IP. |
PAB726Mu02 | Polyclonal Antibody to Cluster Of Differentiation (CD163) | WB; IHC; ICC; IP. | |
LAB726Mu81 | FITC-Linked Polyclonal Antibody to Cluster Of Differentiation (CD163) | WB; IHC; ICC; IF. | |
Assay Kits | SEB726Mu | ELISA Kit for Cluster Of Differentiation (CD163) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
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