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Golgi Phosphoprotein 2 (GOLPH2)

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GOLM1; GP73; C9orf155; Golgi Membrane Protein 1; Golgi Protein 73

Golgi Phosphoprotein 2 (GOLPH2)
CCC B668
HGNC 15451
MGI 1917329
PubMed 21517136
UniProt Q8NBJ4
Wiki GOLM1

  • Golgi protein-73 (GP73), a resident Golgi glycoprotein, is up-regulated in hepatocellular carcinoma (HCC). GP73 is a novel serum marker for HCC.

  • The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. 1 is a type II Golgi transmembrane protein. It processes protein synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this encoded protein has been observed to be upregulated in response to viral infection. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.It is overexpressed in prostate cancer.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB668Hu01 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB668Hu02 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB668Hu03 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB668Hu04 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB668Hu01 Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC; IP.
MAB668Hu22 Monoclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC; IP.
LAB668Hu71 Biotin-Linked Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC.
PAB668Hu02 Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC; IP.
Assay Kits SEB668Hu ELISA Kit for Golgi Phosphoprotein 2 (GOLPH2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB668Mu01 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
RPB668Mu02 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
APB668Mu01 Active Golgi Phosphoprotein 2 (GOLPH2) Cell culture; Activity Assays.
Antibodies PAB668Mu01 Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC; IP; FCM
LAB668Mu81 FITC-Linked Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC; IF.
LAB668Mu71 Biotin-Linked Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC.
PAB668Mu02 Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) WB; IHC; ICC; IP.
Assay Kits SEB668Mu ELISA Kit for Golgi Phosphoprotein 2 (GOLPH2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB668Ra01 Recombinant Golgi Phosphoprotein 2 (GOLPH2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgi Phosphoprotein 2 (GOLPH2) Polyclonal Antibody Customized Service Offer
Assay Kits SEB668Ra ELISA Kit for Golgi Phosphoprotein 2 (GOLPH2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "GP73, a novel Golgi-localized protein upregulated by viral infection."Gene 249:53-65(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption."Traffic 3:641-653(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease."Hepatology 35:1431-1440(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Upregulation of the Golgi protein GP73 by adenovirus infection requires the E1A CtBP interaction domain."Virology 301:236-246(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."J. Proteome Res. 5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
  10. "A strategy for precise and large scale identification of core fucosylated glycoproteins."Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and Golgi organization and is associated with protein secretion pathways critical in bone development."Hum. Mutat. 32:231-239(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]