Interleukin 18 Receptor 1 (IL18R1)
[Edit]CDw218a; CD218a; IL18-R1; IL-1Rrp; IL1RRP; CD218 antigen-like family member A; IL1 receptor-related protein
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interleukin-18 receptor 1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
Northern blot analysis revealed that IL1RRP is expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB652Hu01 | Recombinant Interleukin 18 Receptor 1 (IL18R1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB652Hu02 | Recombinant Interleukin 18 Receptor 1 (IL18R1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPB652Hu03 | Recombinant Interleukin 18 Receptor 1 (IL18R1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB652Hu01 | Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC; IP. |
| MAB652Hu22 | Monoclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC; IP. | |
| PAB652Hu02 | Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC; IP. | |
| LAB652Hu71 | Biotin-Linked Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC. | |
| Assay Kits | SEB652Hu | ELISA Kit for Interleukin 18 Receptor 1 (IL18R1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB652Mu01 | Recombinant Interleukin 18 Receptor 1 (IL18R1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB652Mu02 | Recombinant Interleukin 18 Receptor 1 (IL18R1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB652Mu01 | Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC; IP. |
| PAB652Mu02 | Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC; IP. | |
| LAB652Mu71 | Biotin-Linked Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC. | |
| Assay Kits | n/a | CLIA Kit for Interleukin 18 Receptor 1 (IL18R1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 18 Receptor 1 (IL18R1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB652Ra01 | Recombinant Interleukin 18 Receptor 1 (IL18R1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB652Ra01 | Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Interleukin 18 Receptor 1 (IL18R1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Interleukin 18 Receptor 1 (IL18R1) | ELISA Kit Customized Service Offer |
- "IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP."J. Biol. Chem. 271:3967-3970(1996) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Purification and characterization of the human interleukin-18 receptor."J. Biol. Chem. 272:25737-25742(1997) [PubMed] [Europe PMC] [Abstract]