Bone Marrow Stromal Cell Antigen 1 (BST1)
[Edit]CD157; ADP-Ribosyl Cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
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BST-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.Ferrero et al. found that CD38 and its paralog BST1 (CD157) map to the same 800-kb restriction fragment in pulsed-field gel electrophoresis, indicating that the 2 human ecto-NADase genes are closely linked. Because the CD38 gene maps to 4p15, this information was incompatible with the report of Kaisho et al. , which indicated that BST1 maps to chromosome 14.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB551Mu01 | Recombinant Bone Marrow Stromal Cell Antigen 1 (BST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB551Mu01 | Polyclonal Antibody to Bone Marrow Stromal Cell Antigen 1 (BST1) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Bone Marrow Stromal Cell Antigen 1 (BST1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Bone Marrow Stromal Cell Antigen 1 (BST1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB551Ra01 | Recombinant Bone Marrow Stromal Cell Antigen 1 (BST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB551Ra01 | Polyclonal Antibody to Bone Marrow Stromal Cell Antigen 1 (BST1) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Bone Marrow Stromal Cell Antigen 1 (BST1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Bone Marrow Stromal Cell Antigen 1 (BST1) | ELISA Kit Customized Service Offer |
- "BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth."Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329(1994) [PubMed] [Europe PMC] [Abstract]
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- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
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- "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
- "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
- "Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities."J. Mol. Biol. 316:711-723(2002) [PubMed] [Europe PMC] [Abstract]