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Ornithine Transcarbamylase (OTC)

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OCTD; OCT; OTCase; Ornithine Transcarbamylase; Ornithine Carbamoyltransferase

Ornithine Transcarbamylase (OTC)
CCC B492
HGNC 8512
MGI 97448
PubMed 1528018
RGD 3236
UniProt P00480
Wiki OCT

Ornithine transcarbamoylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi). In plants and microbes OTC is involved in arginine (Arg) biosynthesis, whereas in mammals it is located in the mitochondria and is part of the urea cycle.OTC is a trimer.

The monomer unit has a CP-binding domain and an amino acid-binding domain. Each of the two discrete substrate-binding domains (SBDs) have an alpha/beta; topology with a central beta-pleated sheet embedded in flanking alpha-helices.The active sites are located at the interface between the protein monomers.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB492Hu01 Recombinant Ornithine Transcarbamylase (OTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB492Hu01 Polyclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
MAB492Hu22 Monoclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
Assay Kits SEB492Hu ELISA Kit for Ornithine Transcarbamylase (OTC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB492Mu01 Recombinant Ornithine Transcarbamylase (OTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB492Mu01 Polyclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
Assay Kits SEB492Mu ELISA Kit for Ornithine Transcarbamylase (OTC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB492Ra01 Recombinant Ornithine Transcarbamylase (OTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB492Ra01 Polyclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
MAB492Ra21 Monoclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
Assay Kits SEB492Ra ELISA Kit for Ornithine Transcarbamylase (OTC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB492Bo01 Recombinant Ornithine Transcarbamylase (OTC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB492Bo01 Polyclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
MAB492Bo21 Monoclonal Antibody to Ornithine Transcarbamylase (OTC) WB; IHC; ICC; IP.
Assay Kits SEB492Bo ELISA Kit for Ornithine Transcarbamylase (OTC) Enzyme-linked immunosorbent assay for Antigen Detection.
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