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Glucuronidase Beta (GUSb)

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GUS-B; MPS7; Beta-G1

Glucuronidase Beta (GUSb)
CCC B416
HGNC 4696
MGI 95872
PubMed 6146321
RGD 2772
UniProt P08236
Wiki GUSB

Beta-glucuronidase is an enzyme that in humans is encoded by the GUSB gene.Human beta-glucuronidase is synthesized as an 80 kDa monomer (653 amino acids) before proteolysis removes 18 amino acids from the C-terminal end to form a 78 kDa monomer.  Biologically, beta-glucuronidase exists as a 332 kDa homotetramer.  Beta-glucuronidase contains several notable structural formations, including a type of beta barrel known as a jelly roll barrel and a TIM barrel.

Human beta-glucuronidase is homologous to the Escherichia coli enzyme beta-galactosidase.  This homologous relationship, along with the knowledge that glycosidases often perform hydrolysis catalyzed by two acidic residues, enabled the development of a mechanistic hypothesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB416Hu01 Recombinant Glucuronidase Beta (GUSb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB416Hu01 Polyclonal Antibody to Glucuronidase Beta (GUSb) WB,IHC,ICC/IF
MAB416Hu22 Monoclonal Antibody to Glucuronidase Beta (GUSb) WB; IHC; ICC; IP.
LAB416Hu71 Biotin-Linked Polyclonal Antibody to Glucuronidase Beta (GUSb) WB; IHC; ICC.
Assay Kits SEB416Hu ELISA Kit for Glucuronidase Beta (GUSb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB416Mu01 Recombinant Glucuronidase Beta (GUSb) Positive Control; Immunogen; SDS-PAGE; WB.
RPB416Mu02 Recombinant Glucuronidase Beta (GUSb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB416Mu01 Polyclonal Antibody to Glucuronidase Beta (GUSb) WB; IHC; ICC; IP.
PAB416Mu02 Polyclonal Antibody to Glucuronidase Beta (GUSb) WB; IHC; ICC; IP.
Assay Kits SEB416Mu ELISA Kit for Glucuronidase Beta (GUSb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB416Ra01 Recombinant Glucuronidase Beta (GUSb) Positive Control; Immunogen; SDS-PAGE; WB.
APB416Ra01 Active Glucuronidase Beta (GUSb) Cell culture; Activity Assays.
Antibodies PAB416Ra01 Polyclonal Antibody to Glucuronidase Beta (GUSb) WB; IHC; ICC; IP.
MAB416Ra21 Monoclonal Antibody to Glucuronidase Beta (GUSb) WB; IHC; ICC; IP.
Assay Kits SEB416Ra ELISA Kit for Glucuronidase Beta (GUSb) Enzyme-linked immunosorbent assay for Antigen Detection.
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