Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4)
[Edit]CD85k; LILR-B4; LILRB5; HM18; ILT3; LIR-5; Immunoglobulin-like transcript 3; Leukocyte immunoglobulin-like receptor 5; CD85 antigen-like family member K
Leukocyte immunoglobulin-like receptor subfamily B member 4is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB399Hu01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB399Hu01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | WB; IHC; ICC; IP. |
MAB399Hu22 | Monoclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | WB; IHC; ICC; IP. | |
Assay Kits | SEB399Hu | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB399Mu01 | Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB399Mu01 | Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | WB |
Assay Kits | n/a | CLIA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) | ELISA Kit Customized Service Offer |
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