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Breast Cancer Susceptibility Protein 1 (BRCA1)

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BRCAI; BRCC1; IRIS; PSCP; RNF53; Breast Cancer 1,Early Onset; RING finger protein 53

Breast Cancer Susceptibility Protein 1 (BRCA1)
CCC B376
HGNC 1100
MGI 104537
PubMed 12767038
RGD 2218
UniProt P38398
Wiki BRCA1

BRCA1  is a human gene, some mutations of which are associated with a significant increase in the risk of breast cancer, as well as other cancers. BRCA1 belongs to a class of genes known as tumor suppressors, which maintains genomic integrity to prevent dangerous genetic changes. The multifactorial BRCA1 protein product is involved in DNA damage repair especially error-free repair of DNA double strand breaks, ubiquitination, transcriptional regulation as well as other functions.The BRCA1 protein is directly involved in the repair of damaged DNA. In the nucleus of many types of normal cells, the BRCA1 protein is thought to interact indirectly with RAD51 during repair of DNA double-strand breaks, though the details and significance of this interaction is the subject of debate.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB376Hu01 Recombinant Breast Cancer Susceptibility Protein 1 (BRCA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB376Hu01 Polyclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC; IP.
MAB376Hu22 Monoclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC; IP.
LAB376Hu71 Biotin-Linked Polyclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC.
Assay Kits SEB376Hu ELISA Kit for Breast Cancer Susceptibility Protein 1 (BRCA1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB376Mu01 Recombinant Breast Cancer Susceptibility Protein 1 (BRCA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB376Mu01 Polyclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Breast Cancer Susceptibility Protein 1 (BRCA1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Breast Cancer Susceptibility Protein 1 (BRCA1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB376Ra01 Recombinant Breast Cancer Susceptibility Protein 1 (BRCA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB376Ra01 Polyclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC; IP.
LAB376Ra81 FITC-Linked Polyclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC; IF.
LAB376Ra71 Biotin-Linked Polyclonal Antibody to Breast Cancer Susceptibility Protein 1 (BRCA1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Breast Cancer Susceptibility Protein 1 (BRCA1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Breast Cancer Susceptibility Protein 1 (BRCA1) ELISA Kit Customized Service Offer
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