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The cytokine thymic stromal lymphopoietin (TSLP) drives immature B cell development in vitro and may regulate T helper type 2 responses.Thymic stromal lymphopoietin, also known as TSLP, is a human gene.This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c dendritic cells.
Alternative splicing of this gene results in two transcript variants. TSLP is an interleukin (IL)-7-like cytokine produced by epithelial cells and triggers dendritic cell-mediated Th2 type allergic inflammatory responses.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB320Mu01 | Recombinant Thymic Stromal Lymphopoietin (TSLP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB320Mu02 | Recombinant Thymic Stromal Lymphopoietin (TSLP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPB320Mu03 | Recombinant Thymic Stromal Lymphopoietin (TSLP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPB320Mu04 | Recombinant Thymic Stromal Lymphopoietin (TSLP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB320Mu01 | Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP) | WB; IHC; ICC; IP. |
| PAB320Mu02 | Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB320Mu | ELISA Kit for Thymic Stromal Lymphopoietin (TSLP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB320Ra01 | Recombinant Thymic Stromal Lymphopoietin (TSLP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB320Ra01 | Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP) | WB; IHC; ICC; IP. |
| LAB320Ra71 | Biotin-Linked Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP) | WB; IHC; ICC. | |
| MAB320Ra21 | Monoclonal Antibody to Thymic Stromal Lymphopoietin (TSLP) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB320Ra | ELISA Kit for Thymic Stromal Lymphopoietin (TSLP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation."Leukemia 15:1286-1292(2001) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells."J. Exp. Med. 204:253-258(2007) [PubMed] [Europe PMC] [Abstract]
- "The short form of TSLP is constitutively translated in human keratinocytes and has characteristics of an antimicrobial peptide."Mucosal Immunol. 8:49-56(2015) [PubMed] [Europe PMC] [Abstract]