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Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)

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TNFRSF5; CDW40; Bp50; P50; B-cell surface antigen CD40; CD40L receptor

Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)
CCC B249
HGNC 11919
MGI 88336
PubMed 20473910
RGD 619830
UniProt P25942
Wiki CD40

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB249Hu01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Positive Control; Immunogen; SDS-PAGE; WB.
EPB249Hu61 Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Positive Control; Immunogen; SDS-PAGE; WB.
APB249Hu61 Active Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Cell culture; Activity Assays.
Antibodies PAB249Hu01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
MAB249Hu21 Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB
MAB249Hu22 Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
MAB249Hu23 Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
Assay Kits SEB249Hu ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Enzyme-linked immunosorbent assay for Antigen Detection.
AEB249Hu ELISA Kit for Anti-Tumor Necrosis Factor Receptor Superfamily, Member 5 Antibody (Anti-CD40) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB249Mu01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Positive Control; Immunogen; SDS-PAGE; WB.
RPB249Mu02 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB249Mu01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
PAB249Mu02 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
Assay Kits SEB249Mu ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB249Ra01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB249Ra01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
MAB249Ra21 Monoclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) WB; IHC; ICC; IP.
Assay Kits SEB249Ra ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40) Enzyme-linked immunosorbent assay for Antigen Detection.
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