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Myogenin is a muscle-specific basic-helix-loop-helix (bHLH) transcription factor involved in the coordination of skeletal muscle development and repair. Myogenin is a member of the MyoD family of transcription factors, which also includes MyoD, Myf5, and Mrf4.
In mice, myogenin is essential for the development of functional skeletal muscle. When the DNA coding for myogenin was knocked out of the mouse genome, severe skeletal muscle defects were observed. Mice lacking both copies of myogenin (homozygous-null) suffer from perinatal lethality due to the lack of mature secondary skeletal muscle fibers throughout the body. In cell culture, myogenin can induce myogenesis in a variety of non-muscle cell types.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB109Hu01 | Recombinant Myogenin (MYOG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB109Hu01 | Polyclonal Antibody to Myogenin (MYOG) | WB; IHC; ICC; IP. |
| MAB109Hu22 | Monoclonal Antibody to Myogenin (MYOG) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB109Hu | ELISA Kit for Myogenin (MYOG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB109Mu01 | Recombinant Myogenin (MYOG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB109Mu02 | Recombinant Myogenin (MYOG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB109Mu01 | Polyclonal Antibody to Myogenin (MYOG) | WB; IHC; ICC; IP. |
| PAB109Mu02 | Polyclonal Antibody to Myogenin (MYOG) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB109Mu | ELISA Kit for Myogenin (MYOG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB109Ra01 | Recombinant Myogenin (MYOG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB109Ra01 | Polyclonal Antibody to Myogenin (MYOG) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Myogenin (MYOG) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Myogenin (MYOG) | ELISA Kit Customized Service Offer |
- "Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products."EMBO J. 8:3617-3625(1989) [PubMed] [Europe PMC] [Abstract]
- ErratumEMBO J. 9:592-592(1990)
- "Transcription of the muscle regulatory gene Myf4 is regulated by serum components, peptide growth factors and signaling pathways involving G proteins."J. Cell Biol. 115:905-917(1991) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]