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Alkaline Phosphatase, Intestinal (ALPI)

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CIP; IAP; Calf Intestinal Alkaline Phosphatase

Alkaline Phosphatase, Intestinal (ALPI)
CCC B085
HGNC 437
MGI 87984
PubMed 20536777
RGD 2099
UniProt P09923
Wiki ALPI

Alkaline phosphatase, intestinal also known as ALPI is a type of alkaline phosphatase.The deduced polypeptide showed 86.5% amino acid identity to placental ALP and 56.6% amino acid identity to liver/bone/kidney ALP. Thus, the immunologic cross-reactivity of ALPI and ALPP is perhaps explained.

Calf Intestinal Alkaline Phosphatase (CIP) is an enzyme that catalyzes the 5' phosphate group's removal from DNA. This enzyme is frequently used in DNA sub-cloning, because DNA fragments which lack the 5' phosphoryl termini cannot self-ligate. Preventing self ligation is important both in improving the yield of properly ligated product, and reducing the background of improperly self-ligated contaminant.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB085Hu01 Recombinant Alkaline Phosphatase, Intestinal (ALPI) Positive Control; Immunogen; SDS-PAGE; WB.
RPB085Hu02 Recombinant Alkaline Phosphatase, Intestinal (ALPI) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB085Hu01 Polyclonal Antibody to Alkaline Phosphatase, Intestinal (ALPI) WB; IHC; ICC; IP.
MAB085Hu22 Monoclonal Antibody to Alkaline Phosphatase, Intestinal (ALPI) WB; IHC; ICC; IP.
Assay Kits SEB085Hu ELISA Kit for Alkaline Phosphatase, Intestinal (ALPI) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB085Mu01 Recombinant Alkaline Phosphatase, Intestinal (ALPI) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Alkaline Phosphatase, Intestinal (ALPI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Alkaline Phosphatase, Intestinal (ALPI) Polyclonal Antibody Customized Service Offer
Assay Kits SEB085Mu ELISA Kit for Alkaline Phosphatase, Intestinal (ALPI) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB085Ra01 Recombinant Alkaline Phosphatase, Intestinal (ALPI) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB085Ra01 Polyclonal Antibody to Alkaline Phosphatase, Intestinal (ALPI) WB; IHC; ICC; IP.
MAB085Ra21 Monoclonal Antibody to Alkaline Phosphatase, Intestinal (ALPI) WB; IHC; ICC; IP.
Assay Kits SEB085Ra ELISA Kit for Alkaline Phosphatase, Intestinal (ALPI) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning and sequencing of human intestinal alkaline phosphatase cDNA."Proc. Natl. Acad. Sci. U.S.A. 84:695-698(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Nucleotide and amino acid sequences of human intestinal alkaline phosphatase: close homology to placental alkaline phosphatase."Proc. Natl. Acad. Sci. U.S.A. 84:1234-1238(1987) [PubMed] [Europe PMC] [Abstract]
  3. "Sequence and characterization of the human intestinal alkaline phosphatase gene."J. Biol. Chem. 263:12011-12019(1988) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  7. "Promoter structure of the human intestinal alkaline phosphatase gene."Nucleic Acids Res. 15:10599-10599(1987) [PubMed] [Europe PMC] [Abstract]
  8. "Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases."Gene 60:267-276(1987) [PubMed] [Europe PMC] [Abstract]
  9. "Partial sequencing of human adult, human fetal, and bovine intestinal alkaline phosphatases: comparison with the human placental and liver isozymes."Proc. Natl. Acad. Sci. U.S.A. 83:2368-2372(1986) [PubMed] [Europe PMC] [Abstract]
  10. "Chemical nature of intestinal-type alkaline phosphatase in human kidney."Clin. Chem. 38:2539-2542(1992) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]