1,5-Anhydroglucitol (1,5-AG)

1,5-Anhydroglucitol , also known as 1,5-AG, is used primarily to identify glycemic variability in people with diabetes who have normal or near normal hemoglobin A1c levels.

1,5-Anhydroglucitol is a naturally occurring monosaccharide found in nearly all foods, and once ingested is almost 100% non metabolized. 1,5-Anhydroglucitol values decrease during times of hyperglycemia above 180 mg/dL, and return to normal levels after approximately 2 weeks in the absence of hyperglycemia. Monitoring 1,5-anhydroglucitol in people with either type-1 or type-2 diabetes mellitus can assist diabetic patients in determining if their blood glucose levels are frequently above 180 mg/dL, even in the presence of relatively good hemoglobin A1c levels or blood glucose monitoring.