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Mucin 3 (MUC3)

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MUC3A; Mucin 3A,Intestinal

Mucin 3 (MUC3)
CCC B031
HGNC 7513
MGI 1203527
PubMed 17363302
RGD 3124
UniProt Q02505
Wiki MUC3A

The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation .

MUC3 gene, demonstrating that it encodes a transmembrane mucin and is subject to alternative splicing to a form lacking 1 EGF-like domain and the transmembrane domain. Structural homology of the human MUC3 sequence with that of rat and mouse Muc3 indicated that it is closely related to the rodent proteins and is likely to be involved in ligand binding and intracellular signaling.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB031Hu01 Recombinant Mucin 3 (MUC3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB031Hu02 Recombinant Mucin 3 (MUC3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB031Hu03 Recombinant Mucin 3 (MUC3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB031Hu01 Polyclonal Antibody to Mucin 3 (MUC3) WB; IHC; ICC; IP.
MAB031Hu22 Monoclonal Antibody to Mucin 3 (MUC3) WB; IHC; ICC; IP.
PAB031Hu02 Polyclonal Antibody to Mucin 3 (MUC3) WB; IHC; ICC; IP.
Assay Kits SEB031Hu ELISA Kit for Mucin 3 (MUC3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB031Mu01 Recombinant Mucin 3 (MUC3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB031Mu01 Polyclonal Antibody to Mucin 3 (MUC3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Mucin 3 (MUC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mucin 3 (MUC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB031Ra01 Recombinant Mucin 3 (MUC3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB031Ra01 Polyclonal Antibody to Mucin 3 (MUC3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Mucin 3 (MUC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mucin 3 (MUC3) ELISA Kit Customized Service Offer
  1. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus."J. Biol. Chem. 278:49600-49609(2003) [PubMed] [Europe PMC] [Abstract]
  3. "MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region."J. Biol. Chem. 272:26678-26686(1997) [PubMed] [Europe PMC] [Abstract]
  4. "Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin."Biochem. Biophys. Res. Commun. 263:728-736(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning of cDNAs derived from a novel human intestinal mucin gene."Biochem. Biophys. Res. Commun. 171:407-415(1990) [PubMed] [Europe PMC] [Abstract]
  6. "Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B."Biochem. Biophys. Res. Commun. 275:916-923(2000) [PubMed] [Europe PMC] [Abstract]
  7. "Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease."J. Hum. Genet. 46:5-20(2001) [PubMed] [Europe PMC] [Abstract]
  8. "The MUC3 gene encodes a transmembrane mucin and is alternatively spliced."Biochem. Biophys. Res. Commun. 261:83-89(1999) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]