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Low Density Lipoprotein Receptor (LDLR)

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FH; FHC; Familial Hypercholesterolemia

Low Density Lipoprotein Receptor (LDLR)
CCC B008
HGNC 6547
MGI 96765
PubMed 11668627
RGD 2998
UniProt P01130
Wiki LDL_receptor

The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein that mediates the endocytosis of cholesterol-rich LDL. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants (IDL). Brown and Goldstein won a Nobel Prize for their identification of the Low Density Lipoprotein (LDL) receptor in 1985 whilst they were studying familial hypercholesterolemia.

The LDL receptor can be described as a chimeric protein. It is made up of a number of functionally distinct domains that can function independently of each other.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB008Hu01 Recombinant Low Density Lipoprotein Receptor (LDLR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB008Hu01 Polyclonal Antibody to Low Density Lipoprotein Receptor (LDLR) WB; IHC; ICC; IP.
MAB008Hu22 Monoclonal Antibody to Low Density Lipoprotein Receptor (LDLR) WB; IHC; ICC; IP.
Assay Kits SEB008Hu ELISA Kit for Low Density Lipoprotein Receptor (LDLR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB008Mu01 Recombinant Low Density Lipoprotein Receptor (LDLR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB008Mu02 Recombinant Low Density Lipoprotein Receptor (LDLR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB008Mu01 Polyclonal Antibody to Low Density Lipoprotein Receptor (LDLR) WB; IHC; ICC; IP.
PAB008Mu02 Polyclonal Antibody to Low Density Lipoprotein Receptor (LDLR) WB; IHC; ICC; IP.
Assay Kits SEB008Mu ELISA Kit for Low Density Lipoprotein Receptor (LDLR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB008Ra01 Recombinant Low Density Lipoprotein Receptor (LDLR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB008Ra01 Polyclonal Antibody to Low Density Lipoprotein Receptor (LDLR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Low Density Lipoprotein Receptor (LDLR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Low Density Lipoprotein Receptor (LDLR) ELISA Kit Customized Service Offer
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