In molecular biology, the insulin receptor is a transmembrane receptor that is activated by insulin. It belongs to the large class of tyrosine kinase receptors. Two alpha subunits and two beta subunits make up the insulin receptor. The beta subunits pass through the cellular membrane and are linked by disulfide bonds. The alpha and beta subunits are encoded by a single gene (INSR). The insulin receptor has also recently been designated CD220 .The main activity of activation of the insulin receptor is inducing glucose uptake. For this reason "insulin insensitivity", or a decrease in insulin receptor signaling, leads to diabetes mellitus type 2 - the cells are unable to take up glucose, and the result is hyperglycemia (an increase in circulating glucose), and all the sequelae which result from diabetes.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA895Hu01 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA895Hu02 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA895Hu03 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA895Hu04 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA895Hu05 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA895Hu06 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA895Hu01 | Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC/IF |
MAA895Hu22 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IF | |
PAA895Hu02 | Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
PAA895Hu03 | Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
LAA895Hu71 | Biotin-Linked Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC. | |
LAA895Hu81 | FITC-Linked Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IF. | |
MAA895Hu21 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
MAA895Hu23 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
MAA895Hu24 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC | |
MAA895Hu25 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
MAA895Hu27 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
Assay Kits | AEA895Hu | ELISA Kit for Anti-Insulin Receptor Antibody (Anti-INSR) | Enzyme-linked immunosorbent assay for Antibody Detection. |
SEA895Hu | ELISA Kit for Insulin Receptor (INSR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA895Mu01 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA895Mu01 | Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. |
PAA895Mu02 | Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
LAA895Mu81 | FITC-Linked Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IF. | |
Assay Kits | SEA895Mu | ELISA Kit for Insulin Receptor (INSR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA895Ra01 | Recombinant Insulin Receptor (INSR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA895Ra01 | Polyclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. |
MAA895Ra21 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
MAA895Ra22 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
MAA895Ra23 | Monoclonal Antibody to Insulin Receptor (INSR) | WB; IHC; ICC; IP. | |
Assay Kits | SEA895Ra | ELISA Kit for Insulin Receptor (INSR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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