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Cytochrome C (CYCS)

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Cyt-C; HCS; CYC; CytC

Cytochrome C (CYCS)
CCC A594
HGNC 19986
MGI 88578
PubMed 2849112
RGD 2451
UniProt P99999
Wiki CYCS

Cytochrome c, or cyt c (horse heart: PDB 1HRC) is a small heme protein found loosely associated with the inner membrane of the mitochondrion. It is a soluble protein, unlike other cytochromes, and is an essential component of the electron transfer chain. It is capable of undergoing oxidation and reduction, but does not bind oxygen. It transfers electrons between Complexes III and IV.
Cytochrome c is a highly conserved protein across the spectrum of species, found in plants, animals, and many unicellular organisms. This, along with its small size (molecular weight about 12,000 daltons), makes it useful in studies of evolutionary divergence. Its primary structure consists of a chain of 100 amino acids.
 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA594Hu01 Recombinant Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
RPA594Hu02 Recombinant Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA594Mi01 Polyclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC; IP.
PAA594Hu01 Polyclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC; IP.
MAA594Hu21 Monoclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC/IF
CAA594Mi22 Anti-Cytochrome C (CYCS) Monoclonal Antibody Loading Control of WB
MAA594Hu22 Monoclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC; IP.
Assay Kits SEA594Mi ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA594Hu ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA594Mi01 Recombinant Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
RPA594Mu01 Recombinant Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA594Mi01 Polyclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC; IP.
PAA594Mu01 Polyclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC; IP.
CAA594Mi22 Anti-Cytochrome C (CYCS) Monoclonal Antibody Loading Control of WB
Assay Kits SEA594Mi ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA594Mu ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA594Mi01 Recombinant Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
RPA594Ra01 Recombinant Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA594Ra01 Polyclonal Antibody to Cytochrome C (CYCS) WB; IHC; ICC; IP.
CAA594Mi22 Anti-Cytochrome C (CYCS) Monoclonal Antibody Loading Control of WB
Assay Kits SEA594Mi ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA594Ra ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NPA594Po01 Native Cytochrome C (CYCS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies CAA594Mi22 Anti-Cytochrome C (CYCS) Monoclonal Antibody Loading Control of WB
Assay Kits SEA594Po ELISA Kit for Cytochrome C (CYCS) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The human somatic cytochrome c gene: two classes of processed pseudogenes demarcate a period of rapid molecular evolution."Proc. Natl. Acad. Sci. U.S.A. 85:9625-9629(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The amino acid sequence of human heart cytochrome c."J. Biol. Chem. 237:3575-3576(1962) [PubMed] [Europe PMC] [Abstract]
  8. "Human heart cytochrome c. Chymotryptic peptides, tryptic peptides, and the complete amino acid sequence."J. Biol. Chem. 238:2732-2753(1963) [PubMed] [Europe PMC] [Abstract]
  9. "Cytochrome c in the apoptotic and antioxidant cascades."FEBS Lett. 423:275-280(1998) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Solution structure of reduced recombinant human cytochrome c."Submitted (FEB-2003) to the PDB data bank
  14. "A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia."Nat. Genet. 40:387-389(2008) [PubMed] [Europe PMC] [Abstract]