N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

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NT-Pro-ANP; N-ANP

N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

ANP is a hormone important in maintaining body fluid and sodium homeostasis. In cardiomyocytes, human ANP is synthesized as a 151-amino acid prepropeptide. After the signal peptide is removed by the signal peptidase, pro-ANP is stored in the dense granules of the cell. On stimulation, pro-ANP is released from the dense granules and activated on the cell surface by proteolytic cleavage at residue arginine 98, generating an NH2-terminal propeptide and a 26-amino acid COOH-terminal peptide that is biologically active. Plasma concentration of N-terminal atrial natriuretic peptide (Nt-proANP) is strongly directly related to salt sensitivity.In contrast to Nt-proANP, Nt-proBNP is not related to salt sensitivity. Salt sensitivity, as estimated by Nt-proANP, seems to be reduced in type 2 diabetes. Both N-ANP and N-BNP identifies a greater number of patients at risk of death or heart failure than either peptide alone.

 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA484Hu01 Recombinant N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA484Hu01 Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
MAA484Hu22 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
MAA484Hu21 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB
MAA484Hu23 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
MAA484Hu24 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
MAA484Hu25 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
MAA484Hu27 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
Assay Kits SEA484Hu ELISA Kit for N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA484Mu01 Recombinant N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA484Mu01 Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
Assay Kits SEA484Mu ELISA Kit for N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA484Ra01 Recombinant N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA484Ra02 Recombinant N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA484Ra01 Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
MAA484Ra21 Monoclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
PAA484Ra02 Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) WB; IHC; ICC; IP.
Assay Kits SEA484Ra ELISA Kit for N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP) Enzyme-linked immunosorbent assay for Antigen Detection.